Exemestane is a medication primarily used in the treatment of hormone-receptor-positive breast cancer in postmenopausal women. It serves as an aromatase inhibitor, which means that it functions by reducing the levels of estrogen in the body, a hormone that can promote the growth of certain types of breast tumors.
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How Exemestane Works
Exemestane works by binding to the aromatase enzyme, effectively blocking the conversion of androgens to estrogens. This is important in managing hormone-responsive breast cancer. It may not only shrink existing tumors but can also prevent them from coming back after initial treatment.
Typical Dosage and Administration
- Exemestane is usually taken orally in a dose of 25 mg once daily.
- It is recommended to take the medication after meals to enhance absorption.
- Duration of the treatment typically lasts for 2 to 3 years, depending on individual circumstances.
Potential Side Effects
As with any medication, Exemestane comes with potential side effects, including:
- Hot flashes
- Joint pain
- Fatigue
- Nausea
- Weight gain
Conclusion
Exemestane can be an effective part of a treatment plan for patients dealing with hormone-receptor-positive breast cancer. As always, it is critical to consult with healthcare professionals for personalized advice and to monitor for side effects during treatment.

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